Dysbiosis and intestinal hyperpermeability

bacteria culture
bacteria culture
These are two disorders of the intestinal membrane through which nutrients pass into the body

Intestinal dysbiosis is an imbalance between the families of bacteria that colonize our intestines along this membrane. It is generally caused by a poor diet but can paradoxically also be caused by too much fiber intake (in this case, dysbiosis in the small intestine can spread to the colon; first treat the dysbiosis, then gradually reintroduce fiber).

Signs of intestinal dysbiosis include digestive disorders, anxiety, a tendency to lose weight and infections. It involves a thinner mucus layer, destruction of the tight junctions in the villi of the intestinal wall, malabsorption of nutrients and immune dysregulation.

Dysbiosis can be prevented by consuming enough pre- and probiotics, omega 3, the amino acid glutamine, zinc and vitamin D. In cases of proven dysbiosis that cannot be cured with sufficient intakes of these nutrients, I recommend a protocol for regenerating the intestinal microbiota.

Intestinal hyperpermeability results from degradation of the intestinal wall meshwork, with disruption of its tight junctions which, in principle, selectively allow nutrients and water to pass through, while preventing the passage of undesirable substances. This degradation can occur for a variety of reasons, including untreated dysbiosis or celiac disease.

The intestinal mucosa can then release fragments of intestinal bacteria or allergens into the bloodstream, triggering an immune response. The resulting inflammation damages the intestinal villi, reducing the surface area for nutrient absorption and thus the quantity of nutrients absorbed. These processes are at the root of various pathologies (food allergies, anxiety, fatigue, etc.).

To avoid intestinal hyperpermeability, we also need adequate intakes of pre- and probiotics, omega 3, the amino acid glutamine, zinc and vitamin D. In the case of proven hyperpermeability that does not heal with sufficient intakes of these nutrients, I also recommend following a protocol to regenerate the intestinal microbiota.

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Lab picture by CDC